Abstrakt

6-months Outcome of the Effects of Sacubitril/Valsartan Combination in the Treatment of Chronic Heart Failure

Ulviyya Eyubova Aladdin

Background: In recent years, the European Cardiology Association reports that 26 million people worldwide suffer from heart failure. This figure is increasing every year for a number of reasons (obesity, diabetes, smoking, hypertension, and alcohol).

Purpose: The aim of our study is to investigate clinical changes (complaints, functional class, etc.) and echocardiographic effects in patients with chronic heart failure after six months of treatment with traditional complex treatment of chronic heart failure with the addition of sacubitril/valsartan.

Methods: The study included 30 patients over the age of 61 who suffered from chronic heart failure among the population of Baku, Azerbaijan. (21 males, 9 females, 69.3 ± 1.3 - middle age). The study evaluated the clinical indications and transthoracic echocardiography results of the patients prior to admission of the sacubitril/valsartan complex and 6 months after taking it.

Results: In the evaluation of the results of the echocardiographic examination and clinical indications (complains, functional class and etc.) 6 months after the use of the sacubitril/ valsartan combination in patients, positive changes were found in the majority of patients compared with the indications of previous 6 months.

Conclusion: In the individual statistical analysis of the results revealed, the addition of the sacubitril/valsartan complex to the treatment of patients was improving overall condition of the patients.